A Master student position is available to identify new genes and mutations involved in the pathogenesis of retinal diseases (including retinitis pigmentosa, exudative vitreoretinopathies, macular degeneration, etc.) and to investigate their function in order to better understand the molecular basis of this group of eye diseases and to provide the basis for therapeutic interventions.
In our lab, we focus on the investigation of the molecular pathophysiology of the disease phenotype and how specific mutations can lead to these diseases, which result in visual problems or even blindness in affected patients.
We have found several, potentially disease-causing DNA sequence alterations in different genes of patients, which are now being characterized in more detail. The project involves next generation sequencing (NGS) technology to identify putative disease-relevant sequence variations in patients and families, but also the functional analysis of mutations in vitro.
Nine month to one year.
As soon as possible.
Highly motivated students in the area of biology, biomedical sciences or equivalent are encouraged to send applications. A strong interest in human genetics as well as basic training or practical experience in molecular genetics and molecular biology is an advantage. Please submit your application to the following address:
Prof. Dr. Wolfgang Berger
University of Zurich
Institute of Medical Molecular Genetics